Gene
mbd2
- ID
- ZDB-GENE-030131-9049
- Name
- methyl-CpG binding domain protein 2
- Symbol
- mbd2 Nomenclature History
- Previous Names
-
- wu:fa97f06
- zgc:111862
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MBD2 (methyl-CpG binding domain protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Pfefferli et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | DNA-binding domain superfamily | Methyl-CpG-binding domain protein 2/3, p55-binding region | Methyl-CpG binding protein 2/3, C-terminal domain | Methyl-CpG DNA binding |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZTV3
|
256 |
Interactions and Pathways
No data available
Plasmids
No data available