Gene

tgm1

ID
ZDB-GENE-030131-9032
Name
transglutaminase 1, K polypeptide
Symbol
tgm1 Nomenclature History
Previous Names
  • si:ch73-212e20.3
  • TG1-73 (1)
  • wu:fa97b06 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in peptide cross-linking. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1. Is expressed in second tier layer of breeding tubercle and spinous layer of breeding tubercle. Orthologous to human TGM1 (transglutaminase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tgm1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive congenital ichthyosis 1 Alliance Ichthyosis, congenital, autosomal recessive 1 242300
Associated With tgm1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001102 Transglutaminase, N-terminal
Domain IPR002931 Transglutaminase-like
Domain IPR008958 Transglutaminase, C-terminal
Family IPR023608 Protein-glutamine gamma-glutamyltransferase, animal
Family IPR050779 Protein-glutamine gamma-glutamyltransferases
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR014756 Immunoglobulin E-set
Homologous_superfamily IPR036238 Transglutaminase, C-terminal domain superfamily
Homologous_superfamily IPR036985 Transglutaminase-like superfamily
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Immunoglobulin E-set Immunoglobulin-like fold Papain-like cysteine peptidase superfamily Protein-glutamine gamma-glutamyltransferase, animal Protein-glutamine gamma-glutamyltransferases Transglutaminase, C-terminal Transglutaminase, C-terminal domain superfamily Transglutaminase-like Transglutaminase-like superfamily Transglutaminase, N-terminal
UniProtKB:A0A8M3AV10 734
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tgm1-201 (1) Ensembl 3,008 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations