Gene
ncln
- ID
- ZDB-GENE-030131-8788
- Name
- nicalin
- Symbol
- ncln Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Involved in negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry. Acts upstream of or within enteric nervous system development and regulation of signal transduction. Located in endoplasmic reticulum membrane. Is expressed in central nervous system and intestine. Orthologous to human NCLN (nicalin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65783 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Gui et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Nicalin | Peptidase M28 |
---|---|---|---|
UniProtKB:Q6NZ07
|
572 | ||
UniProtKB:A0A8M2B8R6
|
556 | ||
UniProtKB:A0A8M2B8L1
|
557 |
Interactions and Pathways
No data available
Plasmids
No data available