Gene

ncln

ID
ZDB-GENE-030131-8788
Name
nicalin
Symbol
ncln Nomenclature History
Previous Names
  • ncl1 (1)
  • LOC56926
  • nicalin
  • wu:fb07e09
  • wu:fk52a06
  • zgc:77236 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to enable ribosome binding activity. Involved in determination of left/right asymmetry in lateral mesoderm and negative regulation of nodal signaling pathway. Acts upstream of or within enteric nervous system development and regulation of signal transduction. Located in endoplasmic reticulum membrane. Is expressed in central nervous system and intestine. Orthologous to human NCLN (nicalin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Gui et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ncln Human Ortholog
No data available
Associated With ncln Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007484 Peptidase M28
Family IPR016574 Nicalin
Domain Details Per Protein
Protein Additional Resources Length Nicalin Peptidase M28
UniProtKB:Q6NZ07 InterPro 572
UniProtKB:A0A8M2B8R6 InterPro 556
UniProtKB:A0A8M2B8L1 InterPro 557
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ncln-201 (1) Ensembl 2,560 nt
mRNA ncln-202 (1) Ensembl 2,554 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations