Gene

trps1

ID

ZDB-GENE-030131-8404

Name

trichorhinophalangeal syndrome I

Symbol

trps1 Nomenclature History

Previous Names

wu:fb11b10

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in osteochondrodysplasia; trichorhinophalangeal syndrome type I; and trichorhinophalangeal syndrome type III. Orthologous to human TRPS1 (transcriptional repressor GATA binding 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trps1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
trichorhinophalangeal syndrome type I	Alliance	Trichorhinophalangeal syndrome, type I	190350
trichorhinophalangeal syndrome type III	Alliance	Trichorhinophalangeal syndrome, type III	190351

Associated With trps1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000679	Zinc finger, GATA-type
Domain	IPR013087	Zinc finger C2H2-type
Family	IPR028440	Transcription factor TRPS1
Homologous_superfamily	IPR013088	Zinc finger, NHR/GATA-type