Gene
eef2l2
- ID
- ZDB-GENE-030131-8112
- Name
- eukaryotic translation elongation factor 2, like 2
- Symbol
- eef2l2 Nomenclature History
- Previous Names
-
- fj53d02
- si:ch211-113n10.4
- wu:fj53d02
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have GTPase activity; ribosome binding activity; and translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to localize to cytosol and ribonucleoprotein complex. Human ortholog(s) of this gene implicated in glaucoma and spinocerebellar ataxia type 26. Is expressed in brain and musculature system. Orthologous to human EEF2 (eukaryotic translation elongation factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138521 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR031157 | Tr-type G domain, conserved site |
| Domain | IPR000640 | Elongation factor EFG, domain V-like |
| Domain | IPR000795 | Translational (tr)-type GTP-binding domain |
| Domain | IPR004161 | Translation elongation factor EFTu-like, domain 2 |
| Domain | IPR005225 | Small GTP-binding domain |
| Domain | IPR005517 | Translation elongation factor EFG/EF2, domain IV |
| Domain | IPR041095 | Elongation Factor G, domain II |
| Homologous_superfamily | IPR009000 | Translation protein, beta-barrel domain superfamily |
| Homologous_superfamily | IPR014721 | Small ribosomal subunit protein uS5 domain 2-type fold, subgroup |
| Homologous_superfamily | IPR020568 | Ribosomal protein uS5 domain 2-type superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR035647 | EF-G domain III/V-like |
Domain Details Per Protein
| Protein | Length | EF-G domain III/V-like | Elongation factor EFG, domain V-like | Elongation Factor G, domain II | P-loop containing nucleoside triphosphate hydrolase | Ribosomal protein uS5 domain 2-type superfamily | Small GTP-binding domain | Small ribosomal subunit protein uS5 domain 2-type fold, subgroup | Translational (tr)-type GTP-binding domain | Translation elongation factor EFG/EF2, domain IV | Translation elongation factor EFTu-like, domain 2 | Translation protein, beta-barrel domain superfamily | Tr-type G domain, conserved site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8N7UVM4
|
861 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eef2l2-201
(1)
|
Ensembl | 3,339 nt | ||
| ncRNA |
eef2l2-002
(1)
|
Ensembl | 805 nt | ||
| ncRNA |
eef2l2-003
(1)
|
Ensembl | 674 nt |
Interactions and Pathways
No data available
Plasmids
No data available