Gene
cd2ap
- ID
- ZDB-GENE-030131-8078
- Name
- CD2-associated protein
- Symbol
- cd2ap Nomenclature History
- Previous Names
-
- cd2apl
- fj51c01
- im:7153970
- si:ch211-207n9.1
- wu:fj51c01
- zgc:103705
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Involved in glomerular filtration and pronephric glomerulus development. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis. Orthologous to human CD2AP (CD2 associated protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103705 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| focal segmental glomerulosclerosis 3 | Alliance | Glomerulosclerosis, focal segmental, 3 | 607832 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR035775 | CD2-associated protein, first SH3 domain |
| Domain | IPR035776 | CD2-associated protein, second SH3 domain |
| Domain | IPR035777 | CD2-associated protein, third SH3 domain |
| Family | IPR050384 | Endophilin/SH3RF |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Length | CD2-associated protein, first SH3 domain | CD2-associated protein, second SH3 domain | CD2-associated protein, third SH3 domain | Endophilin/SH3RF | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AKU9
|
655 | ||||||
|
UniProtKB:A0A8M2B7J4
|
607 | ||||||
|
UniProtKB:F1R1N9
|
657 | ||||||
|
UniProtKB:Q5PR31
|
279 |
Interactions and Pathways
No data available
Plasmids
No data available