Gene
ndst1b
- ID
- ZDB-GENE-030131-8022
- Name
- N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b
- Symbol
- ndst1b Nomenclature History
- Previous Names
-
- ndst1
- fj47c03
- wu:fj47c03
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Enables [heparan sulfate]-glucosamine N-sulfotransferase activity. Acts upstream of or within sulfation and vasculogenesis. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including hindbrain; intermediate cell mass of mesoderm; myotome; pectoral fin; and somite. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 46. Orthologous to human NDST1 (N-deacetylase and N-sulfotransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Filipek-Górniok et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Harfouche et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 46 | Alliance | Intellectual developmental disorder, autosomal recessive 46 | 616116 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Heparan sulfate sulfotransferase | Heparan sulphate-N-deacetylase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IR84
|
886 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndst1b-201
(1)
|
Ensembl | 5,805 nt | ||
| mRNA |
ndst1b-202
(1)
|
Ensembl | 5,926 nt |
Interactions and Pathways
No data available
Plasmids
No data available