Gene
osgep
- ID
- ZDB-GENE-030131-7880
- Name
- O-sialoglycoprotein endopeptidase
- Symbol
- osgep Nomenclature History
- Previous Names
-
- fj38e02
- si:ch211-214j24.11 (1)
- wu:fj38e02
- zgc:112527
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to act upstream of or within tRNA processing. Predicted to be located in nucleus. Predicted to be part of EKC/KEOPS complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 3. Orthologous to human OSGEP (O-sialoglycoprotein endopeptidase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112527 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Galloway-Mowat syndrome 3 | Alliance | Galloway-Mowat syndrome 3 | 617729 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017860 | Peptidase M22, conserved site |
| Domain | IPR000905 | Gcp-like domain |
| Family | IPR017861 | Kae1/TsaD family |
| Family | IPR034680 | tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaeal/eukaryotic |
| Homologous_superfamily | IPR043129 | ATPase, nucleotide binding domain |
Domain Details Per Protein
| Protein | Length | ATPase, nucleotide binding domain | Gcp-like domain | Kae1/TsaD family | Peptidase M22, conserved site | tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaeal/eukaryotic |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PUE5
|
335 | |||||
|
UniProtKB:Q5RHZ6
|
335 |
Interactions and Pathways
No data available
Plasmids
No data available