Gene

clpp

ID
ZDB-GENE-030131-7860
Name
caseinolytic mitochondrial matrix peptidase proteolytic subunit
Symbol
clpp Nomenclature History
Previous Names
  • fj37a05
  • si:dkey-204f11.65 (1)
  • wu:fj37a05 (1)
  • zgc:112333
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have ATP-dependent peptidase activity; ATPase binding activity; and serine-type endopeptidase activity. Predicted to be involved in protein quality control for misfolded or incompletely synthesized proteins. Predicted to localize to endopeptidase Clp complex. Human ortholog(s) of this gene implicated in Perrault syndrome. Orthologous to human CLPP (caseinolytic mitochondrial matrix peptidase proteolytic subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With clpp Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Perrault syndrome Alliance Perrault syndrome 3 614129
Associated With clpp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018215 ClpP, Ser active site
Active_site IPR033135 ClpP, histidine active site
Family IPR001907 ATP-dependent Clp protease proteolytic subunit
Family IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA
Homologous_superfamily IPR029045 ClpP/crotonase-like domain superfamily
Domain Details Per Protein
Protein Length ATP-dependent Clp protease proteolytic subunit ClpP/crotonase-like domain superfamily ClpP, histidine active site Clp protease proteolytic subunit /Translocation-enhancing protein TepA ClpP, Ser active site
UniProtKB:Q502B9 266
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA clpp-201 (1) Ensembl 1,497 nt
mRNA clpp-202 (1) Ensembl 694 nt
mRNA clpp-203 (1) Ensembl 1,179 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations