Gene

adgrl3.1

ID

ZDB-GENE-030131-7856

Name

adhesion G protein-coupled receptor L3.1

Symbol

adgrl3.1 Nomenclature History

Previous Names

lphn3.1
lphn3
si:ch211-209p5.2 (1)
wu:fj36g07

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to enable G protein-coupled receptor activity and carbohydrate binding activity. Acts upstream of or within cellular response to estrogen stimulus; habituation; and locomotory exploration behavior. Predicted to be located in membrane. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; eye; heart; liver; and ovary. Orthologous to human ADGRL3 (adhesion G protein-coupled receptor L3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adgrl3.1 Human Ortholog

No data available

Associated With adgrl3.1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR000203	GPS motif
Conserved_site	IPR017983	GPCR, family 2, secretin-like, conserved site
Domain	IPR000922	D-galactoside/L-rhamnose binding SUEL lectin domain
Domain	IPR001879	GPCR, family 2, extracellular hormone receptor domain
Domain	IPR003112	Olfactomedin-like domain
Domain	IPR003334	GPCR, family 2, latrophilin, C-terminal
Domain	IPR017981	GPCR, family 2-like, 7TM
Domain	IPR032471	GAIN domain, N-terminal
Family	IPR000832	GPCR, family 2, secretin-like
Family	IPR003924	GPCR, family 2, latrophilin
Homologous_superfamily	IPR036445	GPCR family 2, extracellular hormone receptor domain superfamily
Homologous_superfamily	IPR043159	D-galactoside/L-rhamnose binding SUEL lectin domain superfamily
Homologous_superfamily	IPR046338	GAIN domain superfamily

Domain Details Per Protein

Protein	Length	D-galactoside/L-rhamnose binding SUEL lectin domain	D-galactoside/L-rhamnose binding SUEL lectin domain superfamily	GAIN domain, N-terminal	GAIN domain superfamily	GPCR, family 2, extracellular hormone receptor domain	GPCR family 2, extracellular hormone receptor domain superfamily	GPCR, family 2, latrophilin	GPCR, family 2, latrophilin, C-terminal	GPCR, family 2-like, 7TM	GPCR, family 2, secretin-like	GPCR, family 2, secretin-like, conserved site	GPS motif	Olfactomedin-like domain
UniProtKB:A0A8M2BI50 InterPro	1539
UniProtKB:A0A8M9Q934 InterPro	1498
UniProtKB:A0A2R8Q6E9 InterPro	1492
UniProtKB:A0A2R8QM07 InterPro	1540
UniProtKB:F1Q579 InterPro	1534

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	adgrl3.1-201 (1) Ensembl	Ensembl	4,629 nt	Select Tool ZFIN BLAST
mRNA	adgrl3.1-202 (1) Ensembl	Ensembl	6,716 nt	Select Tool ZFIN BLAST
mRNA	adgrl3.1-203 (1) Ensembl	Ensembl	5,012 nt	Select Tool ZFIN BLAST
mRNA	adgrl3.1-204 (1) Ensembl	Ensembl	4,251 nt	Select Tool ZFIN BLAST
mRNA	adgrl3.1-205 (1) Ensembl	Ensembl	4,503 nt	Select Tool ZFIN BLAST
mRNA	adgrl3.1-206 (1) Ensembl	Ensembl	4,647 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations