Gene
cdh15
- ID
- ZDB-GENE-030131-780
- Name
- cadherin 15, type 1, M-cadherin (myotubule)
- Symbol
- cdh15 Nomenclature History
- Previous Names
-
- fb48f12
- wu:fb48f12
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable cadherin binding activity and calcium ion binding activity. Predicted to be involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and cell-cell junction organization. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in plasma membrane. Predicted to be part of catenin complex. Predicted to be active in adherens junction. Is expressed in adaxial cell; musculature system; pectoral fin; and somite. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 3. Orthologous to human CDH15 (cadherin 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu141 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Cortés et al., 2003
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 3 | Alliance | Intellectual developmental disorder, autosomal dominant 3 | 612580 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cadherin | Cadherin conserved site | Cadherin-like | Cadherin-like superfamily | Cadherin, Y-type LIR-motif | Catenin binding domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:E9QEL7
|
792 |
Interactions and Pathways
No data available
Plasmids
No data available