Gene

gas6

ID

ZDB-GENE-030131-7773

Name

growth arrest-specific 6

Symbol

gas6 Nomenclature History

Previous Names

fj34a12
wu:fj34a12
zgc:63860

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity. Involved in sprouting angiogenesis. Predicted to localize to extracellular region. Is expressed in heart; nervous system; and neural tube. Orthologous to human GAS6 (growth arrest specific 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

15 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63860 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gas6 Human Ortholog

No data available

Associated With gas6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Domain	IPR000294	Gamma-carboxyglutamic acid-rich (GLA) domain
Domain	IPR000742	EGF-like domain
Domain	IPR001791	Laminin G domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR049883	NOTCH1 EGF-like calcium-binding domain
Family	IPR051145	Growth Arrest-Specific/Sex Hormone-Binding/Vitamin K-Dependent
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR017857	Coagulation factor-like, Gla domain superfamily
Homologous_superfamily	IPR035972	Gamma-carboxyglutamic acid-rich (GLA) domain superfamily
PTM	IPR000152	EGF-type aspartate/asparagine hydroxylation site