Gene

g3bp1

ID

ZDB-GENE-030131-7452

Name

GTPase activating protein (SH3 domain) binding protein 1

Symbol

g3bp1 Nomenclature History

Previous Names

fj17h05
wu:fj17h05
zgc:56034 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Enables mRNA 3'-UTR binding activity. Predicted to act upstream of or within innate immune response. Predicted to be located in cytoplasmic stress granule. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytosol. Is expressed in neuromast. Orthologous to human G3BP1 (G3BP stress granule assembly factor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56034 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With g3bp1 Human Ortholog

No data available

Associated With g3bp1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR002075	Nuclear transport factor 2 domain
Domain	IPR018222	Nuclear transport factor 2, eukaryote
Domain	IPR034374	G3BP1, RNA recognition motif
Family	IPR039539	Ras GTPase-activating protein-binding protein
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR032710	NTF2-like domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	G3BP1, RNA recognition motif	NTF2-like domain superfamily	Nuclear transport factor 2 domain	Nuclear transport factor 2, eukaryote	Nucleotide-binding alpha-beta plait domain superfamily	Ras GTPase-activating protein-binding protein	RNA-binding domain superfamily	RNA recognition motif domain
UniProtKB:A0A8M2BKD5 InterPro	485
UniProtKB:Q7ZVG3 InterPro	477

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	g3bp1-201 (1) Ensembl	Ensembl	1,447 nt	Select Tool ZFIN BLAST
mRNA	g3bp1-202 (1) Ensembl	Ensembl	4,342 nt	Select Tool ZFIN BLAST
mRNA	g3bp1-204 (1) Ensembl	Ensembl	887 nt	Select Tool ZFIN BLAST
mRNA	g3bp1-205 (1) Ensembl	Ensembl	713 nt	Select Tool ZFIN BLAST
mRNA	g3bp1-206 (1) Ensembl	Ensembl	472 nt	Select Tool ZFIN BLAST
ncRNA	g3bp1-004 (1) Ensembl	Ensembl	749 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations