Gene
arpc1b
- ID
- ZDB-GENE-030131-7414
- Name
- actin related protein 2/3 complex, subunit 1B
- Symbol
- arpc1b Nomenclature History
- Previous Names
-
- cb871 (1)
- fj15h02
- wu:fj08e12
- wu:fj15h02
- zgc:64056
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Involved in T cell differentiation and thrombocyte differentiation. Predicted to localize to Arp2/3 protein complex. Human ortholog(s) of this gene implicated in gastritis and myelodysplastic syndrome. Is expressed in blood; blood island; pectoral fin musculature; pharyngeal arch 3-7 skeleton; and ventral wall of dorsal aorta. Orthologous to human ARPC1B (actin related protein 2/3 complex subunit 1B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb871 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Somech et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 71 | Alliance | Immunodeficiency 71 with inflammatory disease and congenital thrombocytopenia | 617718 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Actin-related protein 2/3 complex subunit 1 | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q7T372
|
369 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arpc1b-201
(1)
|
Ensembl | 1,702 nt | ||
| mRNA |
arpc1b-202
(1)
|
Ensembl | 1,129 nt |
Interactions and Pathways
No data available
Plasmids
No data available