Gene
mak
- ID
- ZDB-GENE-030131-7279
- Name
- male germ cell-associated kinase
- Symbol
- mak Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within motile cilium assembly. Predicted to be active in cilium; cytoplasm; and nucleus. Is expressed in Kupffer's vesicle; retina; and retinal photoreceptor layer. Human ortholog(s) of this gene implicated in retinitis pigmentosa 62. Orthologous to human MAK (male germ cell associated kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56603 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 62 | Alliance | Retinitis pigmentosa 62 | 614181 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR050117 | Mitogen-activated protein kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Mitogen-activated protein kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
| UniProtKB:F1QUT2 | InterPro | 633 | |||||
| UniProtKB:A0A8M9PFV2 | InterPro | 590 | |||||
| UniProtKB:A0A8M3ANF8 | InterPro | 600 | |||||
| UniProtKB:A0A8M2B9R2 | InterPro | 601 | |||||
| UniProtKB:Q7ZTX0 | InterPro | 633 | |||||
| UniProtKB:A0A286Y937 | InterPro | 632 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids