Gene

tubb2b

ID
ZDB-GENE-030131-722
Name
tubulin, beta 2b
Symbol
tubb2b Nomenclature History
Previous Names
  • fb40f09
  • wu:fb40f09 (1)
  • zgc:123194
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have GTP binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to localize to cytoplasm and microtubule. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 7. Orthologous to human TUBB2B (tubulin beta 2B class IIb).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tubb2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
complex cortical dysplasia with other brain malformations 7 Alliance Cortical dysplasia, complex, with other brain malformations 7 610031
Associated With tubb2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017975 Tubulin, conserved site
Domain IPR003008 Tubulin/FtsZ, GTPase domain
Domain IPR018316 Tubulin/FtsZ, 2-layer sandwich domain
Family IPR000217 Tubulin
Family IPR002453 Beta tubulin
Homologous_superfamily IPR008280 Tubulin/FtsZ, C-terminal
Homologous_superfamily IPR023123 Tubulin, C-terminal
Homologous_superfamily IPR036525 Tubulin/FtsZ, GTPase domain superfamily
Homologous_superfamily IPR037103 Tubulin/FtsZ-like, C-terminal domain
Domain Details Per Protein
Protein Length Beta tubulin Tubulin Tubulin, conserved site Tubulin, C-terminal Tubulin/FtsZ, 2-layer sandwich domain Tubulin/FtsZ, C-terminal Tubulin/FtsZ, GTPase domain Tubulin/FtsZ, GTPase domain superfamily Tubulin/FtsZ-like, C-terminal domain
UniProtKB:A0A0R4IPH2 445
UniProtKB:A0A8M1N7Z8 472
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tubb2b-201 (1) Ensembl 1,568 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations