Gene

fbp1a

ID

ZDB-GENE-030131-7171

Name

fructose-1,6-bisphosphatase 1a

Symbol

fbp1a Nomenclature History

Previous Names

fbp1l (1)
fk92h02
wu:fk92h02
zgc:64096

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have fructose 1,6-bisphosphate 1-phosphatase activity. Predicted to be involved in several processes, including fructose 1,6-bisphosphate metabolic process; hexose metabolic process; and sucrose biosynthetic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in fructose-1,6-bisphosphatase deficiency. Is expressed in female organism; intestine; lens; and solid lens vesicle. Orthologous to human FBP1 (fructose-bisphosphatase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:64096 (3 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fbp1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
fructose-1,6-bisphosphatase deficiency	Alliance	Fructose-1,6-bisphosphatase deficiency	229700

Associated With fbp1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR020548	Fructose-1,6-bisphosphatase, active site
Domain	IPR033391	Fructose-1-6-bisphosphatase class I, N-terminal
Domain	IPR044015	Fructose-1-6-bisphosphatase class 1, C-terminal
Family	IPR000146	Fructose-1,6-bisphosphatase class 1
Family	IPR028343	Fructose-1,6-bisphosphatase