Gene
mdm4
- ID
- ZDB-GENE-030131-6872
- Name
- MDM4 regulator of p53
- Symbol
- mdm4 Nomenclature History
- Previous Names
-
- wu:fa09h09
- wu:fi33d10
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Predicted to be involved in negative regulation of apoptotic process and negative regulation of cell cycle arrest. Predicted to localize to nucleus. Orthologous to human MDM4 (MDM4 regulator of p53).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:113995 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Bone marrow failure syndrome 6 | 618849 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001876 | Zinc finger, RanBP2-type |
| Domain | IPR003121 | SWIB/MDM2 domain |
| Family | IPR015458 | MDM4 |
| Family | IPR016495 | p53 negative regulator Mdm2/Mdm4 |
| Family | IPR051652 | MDM2/MDM4 and MUL1 |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036443 | Zinc finger, RanBP2-type superfamily |
| Homologous_superfamily | IPR036885 | SWIB/MDM2 domain superfamily |
Domain Details Per Protein
| Protein | Length | MDM2/MDM4 and MUL1 | MDM4 | p53 negative regulator Mdm2/Mdm4 | SWIB/MDM2 domain | SWIB/MDM2 domain superfamily | Zinc finger, RanBP2-type | Zinc finger, RanBP2-type superfamily | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BKM9
|
491 | ||||||||
|
UniProtKB:A0A8M2BK21
|
496 | ||||||||
|
UniProtKB:Q7ZUW7
|
496 |
Interactions and Pathways
No data available
Plasmids
No data available