Gene
mrtfab
- ID
- ZDB-GENE-030131-681
- Name
- myocardin related transcription factor Ab
- Symbol
- mrtfab Nomenclature History
- Previous Names
-
- fb39e12
- mkl1b
- wu:fb39e12
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and smooth muscle cell differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in acute megakaryocytic leukemia and immunodeficiency 66. Orthologous to human MRTFA (myocardin related transcription factor A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 66 | Alliance | ?Immunodeficiency 66 | 618847 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Myocardin-like | RPEL repeat | SAP domain | SAP domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QIR6
|
1217 | ||||
|
UniProtKB:E7F9J6
|
1200 | ||||
|
UniProtKB:A0A8M9QEC1
|
1213 | ||||
|
UniProtKB:A0A8M9QMJ6
|
1188 | ||||
|
UniProtKB:A0A8M9Q8G2
|
1215 | ||||
|
UniProtKB:A0A8M9QIS0
|
1179 | ||||
|
UniProtKB:A0A8M2B2H4
|
1202 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mrtfab-201
(1)
|
Ensembl | 730 nt | ||
| mRNA |
mrtfab-202
(1)
|
Ensembl | 4,810 nt | ||
| mRNA |
mrtfab-203
(1)
|
Ensembl | 501 nt | ||
| mRNA |
mrtfab-204
(1)
|
Ensembl | 873 nt |
Interactions and Pathways
No data available
Plasmids
No data available