Gene
acsl4b
- ID
- ZDB-GENE-030131-6493
- Name
- acyl-CoA synthetase long chain family member 4b
- Symbol
- acsl4b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have catalytic activity. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability. Is expressed in several structures, including digestive system; hatching gland; heart; pleuroperitoneal region; and yolk syncytial layer. Orthologous to human ACSL4 (acyl-CoA synthetase long chain family member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7147969 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Park et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| non-syndromic X-linked intellectual disability 63 | Alliance | Intellectual developmental disorder, X-linked 63 | 300387 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AMP-binding, conserved site | AMP-binding enzyme, C-terminal domain superfamily | AMP-dependent synthetase/ligase domain | ANL, N-terminal domain |
|---|---|---|---|---|---|
|
UniProtKB:A5WV16
|
671 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
acsl4b-201
(1)
|
Ensembl | 3,641 nt | ||
| mRNA |
acsl4b-202
(1)
|
Ensembl | 4,146 nt |
Interactions and Pathways
No data available
Plasmids
No data available