Gene

abcb5

ID

ZDB-GENE-030131-6414

Name

ATP-binding cassette, sub-family B (MDR/TAP), member 5

Symbol

abcb5 Nomenclature History

Previous Names

abcb1a (1)
im:7158730
MDR1 (1)
wu:fc18f02
wu:fi81f06

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable ATPase-coupled transmembrane transporter activity. Acts upstream of or within detoxification of mercury ion. Predicted to be located in membrane. Predicted to be active in apical plasma membrane. Is expressed in several structures, including EVL; integument; liver; periderm; and pleuroperitoneal region. Orthologous to human ABCB5 (ATP binding cassette subfamily B member 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7158730 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcb5 Human Ortholog

No data available

Associated With abcb5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter-like, conserved site
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR011527	ABC transporter type 1, transmembrane domain
Family	IPR039421	Type 1 protein exporter
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036640	ABC transporter type 1, transmembrane domain superfamily

Domain Details Per Protein

Protein	Length	AAA+ ATPase domain	ABC transporter-like, ATP-binding domain	ABC transporter-like, conserved site	ABC transporter type 1, transmembrane domain	ABC transporter type 1, transmembrane domain superfamily	P-loop containing nucleoside triphosphate hydrolase	Type 1 protein exporter
UniProtKB:F1R7A8 InterPro	1338

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	abcb5-201 (1) Ensembl	Ensembl		5,011 nt	Select Tool ZFIN BLAST
mRNA	abcb5-202 (1) Ensembl	Ensembl		8,821 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations