Gene

arid2

ID

ZDB-GENE-030131-6311

Name

AT-rich interactive domain 2

Symbol

arid2 Nomenclature History

Previous Names

fi45a01
si:ch211-132p20.1
wu:fi45a01
zgc:152901

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 6. Orthologous to human ARID2 (AT-rich interaction domain 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arid2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Coffin-Siris syndrome 6	Alliance	Coffin-Siris syndrome 6	617808

Associated With arid2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001606	ARID DNA-binding domain
Domain	IPR003150	DNA-binding RFX-type winged-helix domain
Domain	IPR013087	Zinc finger C2H2-type
Family	IPR052406	Chromatin Remodeling Complex Component
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily
Homologous_superfamily	IPR036431	ARID DNA-binding domain superfamily