Gene

akap13

ID

ZDB-GENE-030131-6253

Name

A-kinase anchoring protein 13

Symbol

akap13 Nomenclature History

Previous Names

si:dkey-187e18.1
wu:fi15d04
wu:fi40d09 (1)
XLOC_170573 (1)

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to enable MAP-kinase scaffold activity. Predicted to be involved in adrenergic receptor signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB signaling; and regulation of Rho protein signal transduction. Predicted to act upstream of or within intracellular signal transduction. Predicted to be located in cytoplasm. Predicted to colocalize with actin cytoskeleton. Is expressed in cardiac ventricle. Orthologous to human AKAP13 (A-kinase anchoring protein 13).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With akap13 Human Ortholog

No data available

Associated With akap13 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000219	Dbl homology (DH) domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain	IPR041020	ARHGEF1-like, PH domain
Family	IPR051632	Rho guanine nucleotide exchange factor
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR035899	Dbl homology (DH) domain superfamily
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Homologous_superfamily	IPR046349	C1-like domain superfamily

Domain Details Per Protein

Protein	Length	Ankyrin repeat-containing domain superfamily	ARHGEF1-like, PH domain	C1-like domain superfamily	Dbl homology (DH) domain	Dbl homology (DH) domain superfamily	PH-like domain superfamily	Pleckstrin homology domain	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Rho guanine nucleotide exchange factor
UniProtKB:A0A0R4IPD6 InterPro
UniProtKB:A0A0R4IYL3 InterPro
UniProtKB:A0A8M9PVD9 InterPro	2517
UniProtKB:A0A8M9PYU5 InterPro	2552
UniProtKB:A0A8M9P6Q8 InterPro	2512
UniProtKB:A0A8M9PH81 InterPro	1069
UniProtKB:A0A8M3AWE0 InterPro	2553
UniProtKB:A0A8M9PVE3 InterPro	2510
UniProtKB:A0A8M9P6Q4 InterPro	2552
UniProtKB:A0A8M9PH76 InterPro	2552
UniProtKB:A0A8M9PVD2 InterPro	2552
UniProtKB:A0A8M9PYV3 InterPro	2533
UniProtKB:A0A8M9PN49 InterPro	1068
UniProtKB:A0A8M3ANY8 InterPro	1475
UniProtKB:A0A8M9PN43 InterPro	2547

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	akap13-201 (1) Ensembl	Ensembl	12,679 nt	Select Tool ZFIN BLAST
mRNA	akap13-203 (1) Ensembl	Ensembl	666 nt	Select Tool ZFIN BLAST
ncRNA	si:dkey-187e18.1-002 (1) Ensembl	Ensembl	680 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations