Gene
ibtk
- ID
- ZDB-GENE-030131-6246
- Name
- inhibitor of Bruton agammaglobulinemia tyrosine kinase
- Symbol
- ibtk Nomenclature History
- Previous Names
-
- fi40c08
- wu:fi40c08
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable protein kinase binding activity and protein tyrosine kinase inhibitor activity. Predicted to be involved in negative regulation of protein phosphorylation. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in telencephalon. Orthologous to human IBTK (inhibitor of Bruton tyrosine kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Diotel et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000210 | BTB/POZ domain |
| Family | IPR051625 | Diverse Signaling and Regulatory Domain-Containing Protein |
| Homologous_superfamily | IPR009091 | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II |
| Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR000408 | Regulator of chromosome condensation, RCC1 |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | BTB/POZ domain | Diverse Signaling and Regulatory Domain-Containing Protein | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II | Regulator of chromosome condensation, RCC1 | SKP1/BTB/POZ domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A286YAJ6
|
1332 |
Interactions and Pathways
No data available
Plasmids
No data available