Gene

isy1

ID
ZDB-GENE-030131-5864
Name
ISY1 splicing factor homolog
Symbol
isy1 Nomenclature History
Previous Names
  • im:7159238
  • rab43
  • wu:fc23h01
  • wu:fi21h07
  • zgc:136785
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to contribute to first spliceosomal transesterification activity. Predicted to be involved in generation of catalytic spliceosome for second transesterification step and mRNA 3'-splice site recognition. Predicted to localize to Prp19 complex and spliceosomal complex. Orthologous to several human genes including ISY1-RAB43 (ISY1-RAB43 readthrough).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With isy1 Human Ortholog
No data available
Associated With isy1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR009360 Pre-mRNA-splicing factor Isy1
Homologous_superfamily IPR029012 Helix hairpin bin domain superfamily
Homologous_superfamily IPR037200 Pre-mRNA-splicing factor Isy1 superfamily
Domain Details Per Protein
Protein Length Helix hairpin bin domain superfamily Pre-mRNA-splicing factor Isy1 Pre-mRNA-splicing factor Isy1 superfamily
UniProtKB:A4FUN5 285
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA isy1-201 (1) Ensembl 2,907 nt
ncRNA isy1-002 (1) Ensembl 842 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
Removed orthology to RAB43 from ZDB-PUB-070523-31. This gene is orthologous to ISY1.
Citations