Gene

rasgef1ba

ID

ZDB-GENE-030131-5783

Name

RasGEF domain family, member 1Ba

Symbol

rasgef1ba Nomenclature History

Previous Names

rasgef1b
wu:fi18a09
zgc:66487

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have Ras guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Is expressed in several structures, including axis; forerunner cell group; germ ring; mesoderm; and nervous system. Orthologous to human RASGEF1B (RasGEF domain family member 1B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66487 (21 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rasgef1ba Human Ortholog

No data available

Associated With rasgef1ba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019804	Ras guanine-nucleotide exchange factor, conserved site
Domain	IPR000651	Ras-like guanine nucleotide exchange factor, N-terminal
Domain	IPR001895	Ras guanine-nucleotide exchange factors catalytic domain
Family	IPR008937	Ras-like guanine nucleotide exchange factor
Homologous_superfamily	IPR023578	Ras guanine nucleotide exchange factor domain superfamily
Homologous_superfamily	IPR036964	Ras guanine-nucleotide exchange factor, catalytic domain superfamily

Domain Details Per Protein

Protein	Length	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Ras guanine-nucleotide exchange factor, conserved site	Ras guanine nucleotide exchange factor domain superfamily	Ras guanine-nucleotide exchange factors catalytic domain	Ras-like guanine nucleotide exchange factor	Ras-like guanine nucleotide exchange factor, N-terminal
UniProtKB:Q6DHR3 InterPro	514
UniProtKB:A0A286YBK7 InterPro	531

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rasgef1ba-201 (1) Ensembl	Ensembl	3,039 nt	Select Tool ZFIN BLAST
mRNA	rasgef1ba-203 (1) Ensembl	Ensembl	2,173 nt	Select Tool ZFIN BLAST
mRNA	rasgef1ba-204 (1) Ensembl	Ensembl	4,454 nt	Select Tool ZFIN BLAST
mRNA	rasgef1ba-205 (1) Ensembl	Ensembl	4,406 nt	Select Tool ZFIN BLAST
ncRNA	rasgef1ba-003 (1) Ensembl	Ensembl	401 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations