Gene

ppp2r2ab

ID

ZDB-GENE-030131-5474

Name

protein phosphatase 2, regulatory subunit B, alpha b

Symbol

ppp2r2ab Nomenclature History

Previous Names

MDS026 (1)
ppp2r2a
ppp2r2d
wu:fd19g04
zgc:63780

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable protein phosphatase regulator activity. Acts upstream of or within blood vessel lumenization. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol. Orthologous to human PPP2R2A (protein phosphatase 2 regulatory subunit Balpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7144038 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ppp2r2ab Human Ortholog

No data available

Associated With ppp2r2ab Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018067	Protein phosphatase 2A regulatory subunit PR55, conserved site
Family	IPR000009	Protein phosphatase 2A regulatory subunit PR55
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	Protein phosphatase 2A regulatory subunit PR55	Protein phosphatase 2A regulatory subunit PR55, conserved site	WD40 repeat	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q6PGU9 InterPro	448
UniProtKB:A2BG80 InterPro	448

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ppp2r2ab-201 (1) Ensembl	Ensembl	1,890 nt	Select Tool ZFIN BLAST
mRNA	ppp2r2ab-202 (1) Ensembl	Ensembl	2,199 nt	Select Tool ZFIN BLAST
ncRNA	ppp2r2ab-002 (1) Ensembl	Ensembl	566 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations