Gene
kdm5ba
- ID
- ZDB-GENE-030131-5379
- Name
- lysine demethylase 5Ba
- Symbol
- kdm5ba Nomenclature History
- Previous Names
-
- id:ibd5050
- jarid1b
- jarid1ba
- wu:fd15c05
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable histone demethylase activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within chromatin organization. Predicted to be active in nucleus. Is expressed in neural rod; paraxial mesoderm; pronephric duct; tail bud; and telencephalon. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 65; breast cancer; and high grade glioma. Orthologous to human KDM5B (lysine demethylase 5B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 65 | Alliance | Intellectual developmental disorder, autosomal recessive 65 | 618109 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001606 | ARID DNA-binding domain |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR003347 | JmjC domain |
| Domain | IPR003349 | JmjN domain |
| Domain | IPR004198 | Zinc finger, C5HC2-type |
| Domain | IPR013637 | Lysine-specific demethylase-like domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR047978 | Lysine-specific demethylase 5B, first PHD-finger |
| Domain | IPR047979 | Lysine-specific demethylase 5B, third PHD-finger |
| Domain | IPR048615 | Lysine-specific demethylase 5, C-terminal helical domain |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036431 | ARID DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | ARID DNA-binding domain | ARID DNA-binding domain superfamily | JmjC domain | JmjN domain | Lysine-specific demethylase 5B, first PHD-finger | Lysine-specific demethylase 5B, third PHD-finger | Lysine-specific demethylase 5, C-terminal helical domain | Lysine-specific demethylase-like domain | Zinc finger, C5HC2-type | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A5WUR6
|
1477 | ||||||||||||||
|
UniProtKB:A0A8M9Q713
|
1478 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kdm5ba-201
(1)
|
Ensembl | 5,330 nt | ||
| mRNA |
kdm5ba-202
(1)
|
Ensembl | 425 nt | ||
| mRNA |
kdm5ba-203
(1)
|
Ensembl | 5,677 nt |
Interactions and Pathways
No data available
Plasmids
No data available