Gene

chaf1a

ID

ZDB-GENE-030131-5366

Name

chromatin assembly factor 1, subunit A (p150)

Symbol

chaf1a Nomenclature History

Previous Names

wu:fd14g10
zgc:153930

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to be involved in nucleosome assembly. Predicted to localize to CAF-1 complex and nucleus. Human ortholog(s) of this gene implicated in colon cancer; malignant glioma; neuroblastoma; and systemic lupus erythematosus. Is expressed in several structures, including eye; pectoral fin; pharyngeal arch 3-7 skeleton; somite; and ventricular zone. Orthologous to human CHAF1A (chromatin assembly factor 1 subunit A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7149897 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With chaf1a Human Ortholog

No data available

Associated With chaf1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR021644	Chromatin assembly factor 1 p150 subunit, acidic region
Domain	IPR022043	Chromatin assembly factor 1 subunit A, dimerization domain
Domain	IPR029091	Chromatin assembly factor 1 subunit p150, N-terminal
Domain	IPR029105	Chromatin assembly factor 1 subunit p150, C-terminal