Gene
hlx1
- ID
- ZDB-GENE-030131-5304
- Name
- H2.0-like homeo box 1 (Drosophila)
- Symbol
- hlx1 Nomenclature History
- Previous Names
-
- fa28a07
- wu:fa28a07
- zgc:76923
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have sequence-specific DNA binding activity. Involved in hematopoietic progenitor cell differentiation and sprouting angiogenesis. Predicted to localize to nucleus. Is expressed in several structures, including axis; brain; cardiovascular system; digestive system; and prechordal plate. Orthologous to human HLX (H2.0 like homeobox).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:76923 (12 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000047 | Helix-turn-helix motif |
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR020479 | Homeodomain, metazoa |
| Family | IPR052497 | H2.0 Homeobox Transcription Factors |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
Domain Details Per Protein
| Protein | Length | H2.0 Homeobox Transcription Factors | Helix-turn-helix motif | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B4D8
|
357 | ||||||
|
UniProtKB:Q6NY96
|
327 | ||||||
|
UniProtKB:A0A8M2BHM6
|
300 |
Interactions and Pathways
No data available
Plasmids
No data available