Gene
rpl5a
- ID
- ZDB-GENE-030131-5161
- Name
- ribosomal protein L5a
- Symbol
- rpl5a Nomenclature History
- Previous Names
-
- rpl5l
- mg:cb01f08
- zgc:77176
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have 5S rRNA binding activity. Involved in chordate embryonic development. Predicted to localize to cytosolic large ribosomal subunit. Used to study Diamond-Blackfan anemia. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia; T-cell acute lymphoblastic leukemia; and glioblastoma multiforme. Is expressed in intestine; liver; and pancreas. Orthologous to human RPL5 (ribosomal protein L5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6909214 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Diamond-Blackfan anemia 6 | Alliance | Diamond-Blackfan anemia 6 | 612561 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Diamond-Blackfan anemia | AB + MO1-rpl5a | standard conditions | Wan et al., 2016 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Large ribosomal subunit protein uL18, C-terminal, eukaryotes | Large ribosomal subunit protein uL18 eukaryotic/archaeal |
|---|---|---|---|
|
UniProtKB:Q7ZUI0
|
297 |
Interactions and Pathways
No data available
Plasmids
No data available