Gene
pif1
- ID
- ZDB-GENE-030131-4928
- Name
- PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
- Symbol
- pif1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including 5'-3' DNA helicase activity; ATP binding activity; and DNA binding activity. Predicted to be involved in DNA recombination; DNA repair; and mitochondrial genome maintenance. Predicted to act upstream of or within cellular response to DNA damage stimulus and telomere maintenance. Predicted to be located in mitochondrion and nucleus. Is expressed in ectoderm; head; optic tectum; pectoral fin musculature; and proliferative region. Orthologous to human PIF1 (PIF1 5'-to-3' DNA helicase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb934 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | DNA helicase Pif1-like, 2B domain | DNA helicase PIF1/RRM3/pfh1 | PIF1 DNA helicase | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZV90
|
639 |
Interactions and Pathways
No data available
Plasmids
No data available