Gene
dgat1a
- ID
- ZDB-GENE-030131-4600
- Name
- diacylglycerol O-acyltransferase 1a
- Symbol
- dgat1a Nomenclature History
- Previous Names
-
- dgat1
- DGAT1B (1)
- wu:fd36g11
- zgc:77691
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable diacylglycerol O-acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in gut; liver; and muscle. Human ortholog(s) of this gene implicated in cardiomyopathy and congenital diarrhea 7 with exudative enteropathy. Orthologous to human DGAT1 (diacylglycerol O-acyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77691 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital diarrhea 7 with exudative enteropathy | Alliance | Diarrhea 7, protein-losing enteropathy type | 615863 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Diacylglycerol O-acyltransferase 1 | Membrane bound O-acyl transferase, MBOAT | Sterol O-acyltransferase, ACAT/DAG/ARE types |
|---|---|---|---|---|
|
UniProtKB:Q6P3J0
|
499 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dgat1a-201
(1)
|
Ensembl | 2,730 nt |
Interactions and Pathways
No data available
Plasmids
No data available