Gene

daam1b

ID

ZDB-GENE-030131-4212

Name

dishevelled associated activator of morphogenesis 1b

Symbol

daam1b Nomenclature History

Previous Names

daam1l
fc83b10
si:ch211-87i20.1 (1)
wu:fc83b10

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have Rho GTPase binding activity and actin binding activity. Involved in convergent extension. Predicted to localize to stress fiber. Is expressed in axis; notochord; and polster. Orthologous to human DAAM1 (dishevelled associated activator of morphogenesis 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2005

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu475 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Kida et al., 2007
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With daam1b Human Ortholog

No data available

Associated With daam1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR010472	Formin, FH3 domain
Domain	IPR010473	Formin, GTPase-binding domain
Domain	IPR014767	Diaphanous autoregulatory (DAD) domain
Domain	IPR014768	Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
Domain	IPR015425	Formin, FH2 domain
Family	IPR051425	Formin Homology
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR042201	Formin, FH2 domain superfamily

Domain Details Per Protein

Protein	Length	Armadillo-like helical	Armadillo-type fold	Diaphanous autoregulatory (DAD) domain	Formin, FH2 domain	Formin, FH2 domain superfamily	Formin, FH3 domain	Formin, GTPase-binding domain	Formin Homology	Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
UniProtKB:B3DJI0 InterPro	1069
UniProtKB:Q5RHJ3 InterPro	1079

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	daam1b-201 (1) Ensembl	Ensembl	3,948 nt	Select Tool
mRNA	daam1b-202 (1) Ensembl	Ensembl	3,359 nt	Select Tool ZFIN BLAST
mRNA	daam1b-205 (1) Ensembl	Ensembl	3,240 nt	Select Tool ZFIN BLAST
ncRNA	daam1b-002 (1) Ensembl	Ensembl	515 nt	Select Tool
ncRNA	daam1b-003 (1) Ensembl	Ensembl	459 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations