Gene
wdr12
- ID
- ZDB-GENE-030131-371
- Name
- WD repeat domain 12
- Symbol
- wdr12 Nomenclature History
- Previous Names
-
- fb24f09
- wu:fb24f09
- YTM1
- zgc:55609
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have ribonucleoprotein complex binding activity. Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and regulation of cell cycle. Predicted to localize to PeBoW complex; nucleoplasm; and preribosome, large subunit precursor. Is expressed in several structures, including immature eye; musculature system; nervous system; neural plate; and segmental plate. Orthologous to human WDR12 (WD repeat domain 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55609 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR012972 | NLE |
| Family | IPR028599 | WD repeat WDR12/Ytm1 |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein beta WD-40 repeat | NLE | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | WD repeat WDR12/Ytm1 |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NX08
|
422 | |||||||
|
UniProtKB:B2GTD1
|
422 |
Interactions and Pathways
No data available
Plasmids
No data available