Gene
usp7
- ID
- ZDB-GENE-030131-3656
- Name
- ubiquitin specific peptidase 7 (herpes virus-associated)
- Symbol
- usp7 Nomenclature History
- Previous Names
-
- fc48f04
- wu:fc48f04
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have cysteine-type endopeptidase activity; thiol-dependent ubiquitin-specific protease activity; and transcription factor binding activity. Involved in cranial skeletal system development. Predicted to localize to cytosol and nucleus. Orthologous to human USP7 (ubiquitin specific peptidase 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7155505 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Hao-Fountain syndrome | 616863 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018200 | Ubiquitin specific protease, conserved site |
| Domain | IPR001394 | Peptidase C19, ubiquitin carboxyl-terminal hydrolase |
| Domain | IPR002083 | MATH/TRAF domain |
| Domain | IPR024729 | Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain |
| Domain | IPR028889 | Ubiquitin specific protease domain |
| Domain | IPR029346 | Ubiquitin carboxyl-terminal hydrolase, C-terminal |
| Family | IPR050164 | Ubiquitin carboxyl-terminal hydrolases |
| Homologous_superfamily | IPR008974 | TRAF-like |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Length | MATH/TRAF domain | Papain-like cysteine peptidase superfamily | Peptidase C19, ubiquitin carboxyl-terminal hydrolase | TRAF-like | Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain | Ubiquitin carboxyl-terminal hydrolase, C-terminal | Ubiquitin carboxyl-terminal hydrolases | Ubiquitin specific protease, conserved site | Ubiquitin specific protease domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q474
|
1086 | |||||||||
|
UniProtKB:A0A8M3AQW7
|
1123 | |||||||||
|
UniProtKB:A0A8M3B0Y8
|
1096 | |||||||||
|
UniProtKB:A0A8M3B8A7
|
1130 | |||||||||
|
UniProtKB:I3ISS5
|
1103 | |||||||||
|
UniProtKB:F1QUS9
|
1110 |
Interactions and Pathways
No data available
Plasmids
No data available