Gene
cdc42bpb
- ID
- ZDB-GENE-030131-3647
- Name
- CDC42 binding protein kinase beta (DMPK-like)
- Symbol
- cdc42bpb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in actomyosin structure organization. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in lamellipodium. Predicted to be active in cytoplasm and cytoskeleton. Orthologous to human CDC42BPB (CDC42 binding protein kinase beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Chilton-Okur-Chung neurodevelopmental syndrome | 619841 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000095 | CRIB domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR001180 | Citron homology (CNH) domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR014930 | Myotonic dystrophy protein kinase, coiled coil |
| Domain | IPR017892 | Protein kinase, C-terminal |
| Domain | IPR031597 | KELK-motif containing domain |
| Family | IPR050839 | Rho-associated Serine/Threonine Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | C1-like domain superfamily | Citron homology (CNH) domain | CRIB domain | KELK-motif containing domain | Myotonic dystrophy protein kinase, coiled coil | PH-like domain superfamily | Pleckstrin homology domain | Protein kinase, ATP binding site | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Protein kinase, C-terminal | Protein kinase domain | Protein kinase-like domain superfamily | Rho-associated Serine/Threonine Kinase | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PBW0
|
1772 | |||||||||||||||
|
UniProtKB:Q5TZ42
|
1708 | |||||||||||||||
|
UniProtKB:A0A8M3AT38
|
1725 | |||||||||||||||
|
UniProtKB:A0A8M9P2Q2
|
1789 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cdc42bpb-201
(1)
|
Ensembl | 6,650 nt | ||
| mRNA |
cdc42bpb-202
(1)
|
Ensembl | 5,919 nt |
Interactions and Pathways
No data available
Plasmids
No data available