Gene

wdr81

ID
ZDB-GENE-030131-3389
Name
WD repeat domain 81
Symbol
wdr81 Nomenclature History
Previous Names
  • fc37g06
  • wu:fc37g06
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have phosphatidylinositol 3-kinase regulator activity. Predicted to be involved in aggrephagy; early endosome to late endosome transport; and ubiquitin-dependent protein catabolic process. Predicted to localize to autophagosome membrane; cytosol; and endosome membrane. Human ortholog(s) of this gene implicated in cerebellar ataxia, mental retardation and dysequlibrium syndrome and hydrocephalus. Is expressed in several structures, including heart; liver; nervous system; optic vesicle; and pleuroperitoneal region. Orthologous to human WDR81 (WD repeat domain 81).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wdr81 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 2 Alliance Cerebellar ataxia, impaired intellectual development, and dysquilibrium syndrome 2 610185
Hydrocephalus, congenital, 3, with brain anomalies 617967
Associated With wdr81 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA wdr81-201 (1) Ensembl 8,249 nt
mRNA wdr81-202 (1) Ensembl 6,198 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations