Gene
pabpc1a
- ID
- ZDB-GENE-030131-3238
- Name
- poly(A) binding protein, cytoplasmic 1a
- Symbol
- pabpc1a Nomenclature History
- Previous Names
-
- pabpc1
- wu:fb16a02
- wu:fc31e01
- wu:fi19b08
- wu:fj12d09
- wu:fj61f06
- zgc:109879
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Acts upstream of or within heart development. Predicted to be located in cytoplasm. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasmic stress granule; cytosol; and nucleus. Is expressed in several structures, including blastodisc; digestive system; eye; pectoral fin bud; and ventral mesenchyme. Orthologous to several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151399 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR002004 | Polyadenylate-binding protein/Hyperplastic disc protein |
| Domain | IPR003954 | RNA recognition motif domain, eukaryote |
| Domain | IPR034364 | PABP, RNA recognition motif 1 |
| Domain | IPR045305 | PABP, RNA recognition motif 2 |
| Family | IPR006515 | Polyadenylate binding protein, human types 1, 2, 3, 4 |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
| Homologous_superfamily | IPR036053 | PABC (PABP) domain |
Domain Details Per Protein
| Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | PABC (PABP) domain | PABP, RNA recognition motif 1 | PABP, RNA recognition motif 2 | Polyadenylate binding protein, human types 1, 2, 3, 4 | Polyadenylate-binding protein/Hyperplastic disc protein | RNA-binding domain superfamily | RNA recognition motif domain | RNA recognition motif domain, eukaryote |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QB54
|
634 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pabpc1a-201
(1)
|
Ensembl | 2,554 nt | ||
| mRNA |
pabpc1a-202
(1)
|
Ensembl | 2,033 nt | ||
| ncRNA |
pabpc1a-003
(1)
|
Ensembl | 539 nt | ||
| ncRNA |
pabpc1a-004
(1)
|
Ensembl | 660 nt | ||
| ncRNA |
pabpc1a-005
(1)
|
Ensembl | 330 nt | ||
| ncRNA |
pabpc1a-006
(1)
|
Ensembl | 747 nt |
Interactions and Pathways
No data available
Plasmids
No data available