Gene

usp19

ID

ZDB-GENE-030131-3055

Name

ubiquitin specific peptidase 19

Symbol

usp19 Nomenclature History

Previous Names

si:dkey-32e6.9
wu:fc26a05 (1)

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable cysteine-type deubiquitinase activity and metal ion binding activity. Acts upstream of or within central nervous system morphogenesis. Predicted to be located in membrane. Orthologous to human USP19 (ubiquitin specific peptidase 19).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Tse et al., 2009
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With usp19 Human Ortholog

No data available

Associated With usp19 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018200	Ubiquitin specific protease, conserved site
Domain	IPR001394	Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain	IPR002893	Zinc finger, MYND-type
Domain	IPR007052	CS domain
Domain	IPR028889	Ubiquitin specific protease domain
Family	IPR050185	Ubiquitin carboxyl-terminal hydrolase
Homologous_superfamily	IPR008978	HSP20-like chaperone
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily

Domain Details Per Protein

Protein	Length	CS domain	HSP20-like chaperone	Papain-like cysteine peptidase superfamily	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase	Ubiquitin specific protease, conserved site	Ubiquitin specific protease domain	Zinc finger, MYND-type
UniProtKB:A0A8M9P5F2 InterPro	1435
UniProtKB:F1RCS0 InterPro	1436
UniProtKB:A0A8M2B8X8 InterPro	1483
UniProtKB:A0A8M2B997 InterPro	1485

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	usp19-201 (1) Ensembl	Ensembl	4,311 nt	Select Tool ZFIN BLAST
mRNA	usp19-202 (1) Ensembl	Ensembl	1,493 nt	Select Tool ZFIN BLAST
mRNA	usp19-203 (1) Ensembl	Ensembl	5,123 nt	Select Tool ZFIN BLAST
mRNA	usp19-204 (1) Ensembl	Ensembl	4,437 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations