Gene

fanci

ID

ZDB-GENE-030131-2905

Name

FA complementation group I

Symbol

fanci Nomenclature History

Previous Names

fc21c10
wu:fc21c10
zgc:152941

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have DNA polymerase binding activity. Predicted to be involved in DNA repair. Human ortholog(s) of this gene implicated in Fanconi anemia and Fanconi anemia complementation group I. Is expressed in central nervous system; head; heart; pectoral fin; and rostral blood island. Orthologous to human FANCI (FA complementation group I).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Titus et al., 2009

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Ramanagoudr-Bhojappa et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fanci Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Fanconi anemia complementation group I	Alliance	Fanconi anemia, complementation group I	609053

Associated With fanci Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR029305	FANCI solenoid 1 cap
Domain	IPR029308	FANCI solenoid 1 domain
Domain	IPR029310	FANCI helical domain 1
Domain	IPR029312	FANCI helical domain 2
Domain	IPR029313	FANCI solenoid 3 domain
Domain	IPR029314	FANCI solenoid 4 domain
Domain	IPR029315	FANCI solenoid 2 domain
Family	IPR026171	Fanconi anemia group I protein