Gene

arrb2a

ID

ZDB-GENE-030131-29

Name

arrestin, beta 2a

Symbol

arrb2a Nomenclature History

Previous Names

ARRB2b1 (1)
fc14e09
hm:zeh0294
wu:fc14e09
zeh0294
zgc:66353

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have angiotensin receptor binding activity. Involved in regulation of chemokine activity and regulation of receptor recycling. Predicted to localize to cytoplasm. Is expressed in presumptive segmental plate; somite; and tail bud. Orthologous to human ARRB2 (arrestin beta 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66353 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Mahabaleshwar et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arrb2a Human Ortholog

No data available

Associated With arrb2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017864	Arrestin, conserved site
Domain	IPR011021	Arrestin-like, N-terminal
Domain	IPR011022	Arrestin C-terminal-like domain
Family	IPR000698	Arrestin
Homologous_superfamily	IPR014752	Arrestin-like, C-terminal
Homologous_superfamily	IPR014753	Arrestin, N-terminal
Homologous_superfamily	IPR014756	Immunoglobulin E-set

Domain Details Per Protein

Protein	Length	Arrestin	Arrestin, conserved site	Arrestin C-terminal-like domain	Arrestin-like, C-terminal	Arrestin-like, N-terminal	Arrestin, N-terminal	Immunoglobulin E-set
UniProtKB:A0A286YBG8 InterPro	414
UniProtKB:Q6PFK2 InterPro	406

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	arrb2a-201 (1) Ensembl	Ensembl	2,008 nt	Select Tool
mRNA	arrb2a-203 (1) Ensembl	Ensembl	1,717 nt	Select Tool ZFIN BLAST
ncRNA	arrb2a-002 (1) Ensembl	Ensembl	846 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations