Gene
sgk1
- ID
- ZDB-GENE-030131-2860
- Name
- serum/glucocorticoid regulated kinase 1
- Symbol
- sgk1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have potassium channel regulator activity and protein serine/threonine kinase activity. Involved in inflammatory response. Predicted to localize to endoplasmic reticulum and nucleus. Human ortholog(s) of this gene implicated in hypertension. Is expressed in several structures, including blood vasculature; epidermal cell; epiphysis; pronephric duct; and ventral mesoderm. Orthologous to human SGK1 (serum/glucocorticoid regulated kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1083 (17 images)
- IMAGE:6912555 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR017892 | Protein kinase, C-terminal |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | Protein kinase, ATP binding site | Protein kinase, C-terminal | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B9J1
|
414 | ||||||
|
UniProtKB:Q7ZTW4
|
433 | ||||||
|
UniProtKB:A0A8M2B972
|
415 | ||||||
|
UniProtKB:A0A8M2B9E4
|
598 |
Interactions and Pathways
No data available
Plasmids
No data available