Gene
dyrk2
- ID
- ZDB-GENE-030131-2804
- Name
- dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
- Symbol
- dyrk2 Nomenclature History
- Previous Names
-
- fc18c09
- si:ch211-266a5.8
- wu:fa09g03
- wu:fc18c09
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation and peptidyl-threonine phosphorylation. Predicted to localize to cytoplasm; cytoskeleton; and nucleus. Is expressed in central nervous system; myotome; and spinal cord. Orthologous to human DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Tanaka et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR050494 | Serine/threonine and dual-specificity kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR042521 | Dual specificity tyrosine-phosphorylation-regulated kinase |
Domain Details Per Protein
| Protein | Length | Dual specificity tyrosine-phosphorylation-regulated kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine and dual-specificity kinase | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4ITS5
|
598 | ||||||
|
UniProtKB:Q5RHV3
|
587 | ||||||
|
UniProtKB:A0A2R8QCS7
|
577 |
Interactions and Pathways
No data available
Plasmids
No data available