Gene

hcfc1b

ID

ZDB-GENE-030131-2411

Name

host cell factor C1b

Symbol

hcfc1b Nomenclature History

Previous Names

fc07b09
fe17f08
wu:fc07b09
wu:fe17f08

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to contribute to histone acetyltransferase activity. Involved in chondrocyte differentiation and embryonic viscerocranium morphogenesis. Predicted to localize to Ada2/Gcn5/Ada3 transcription activator complex. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human HCFC1 (host cell factor C1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hcfc1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
methylmalonic acidemia and homocysteinemia cblX type	Alliance	Methylmalonic aciduria and homocysteinemia, cblX type	309541

Associated With hcfc1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003961	Fibronectin type III
Family	IPR043536	Host cell factor
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR015915	Kelch-type beta propeller
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Repeat	IPR006652	Kelch repeat type 1