Gene

vps35

ID
ZDB-GENE-030131-2042
Name
VPS35 retromer complex component
Symbol
vps35 Nomenclature History
Previous Names
  • si:rp71-34g2.3
  • wu:fa66e03
  • wu:fb95c08 (1)
  • zgc:136268
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to be involved in intracellular protein transport and retrograde transport, endosome to Golgi. Predicted to localize to late endosome and retromer complex. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 17. Orthologous to human VPS35 (VPS35 retromer complex component).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vps35 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Parkinson's disease 17 Alliance {Parkinson disease 17} 614203
Associated With vps35 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR005378 Vacuolar protein sorting-associated protein 35
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR042491 Vacuolar protein sorting-associated protein 35, C-terminal
Domain Details Per Protein
Protein Length Armadillo-type fold Vacuolar protein sorting-associated protein 35 Vacuolar protein sorting-associated protein 35, C-terminal
UniProtKB:A4QP42 796
UniProtKB:Q1ED30 796
UniProtKB:Q6ZM34 831
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA vps35-201 (1) Ensembl 3,573 nt
mRNA vps35-203 (1) Ensembl 752 nt
ncRNA vps35-002 (1) Ensembl 763 nt
ncRNA vps35-004 (1) Ensembl 646 nt
ncRNA vps35-005 (1) Ensembl 701 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations