Gene

gtf2h2

ID

ZDB-GENE-030131-1959

Name

general transcription factor IIH, polypeptide 2

Symbol

gtf2h2 Nomenclature History

Previous Names

p44 (1)
wu:fb93b01

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in nucleotide-excision repair and regulation of transcription by RNA polymerase II. Predicted to localize to transcription factor TFIIH holo complex. Orthologous to several human genes including GTF2H2C (GTF2H2 family member C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55599 (1 image)
IMAGE:7162001 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gtf2h2 Human Ortholog

No data available

Associated With gtf2h2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002035	von Willebrand factor, type A
Domain	IPR004595	TFIIH C1-like domain
Domain	IPR007198	Ssl1-like
Domain	IPR013087	Zinc finger C2H2-type
Family	IPR012170	TFIIH subunit Ssl1/p44
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR036465	von Willebrand factor A-like domain superfamily
Homologous_superfamily	IPR046349	C1-like domain superfamily

Domain Details Per Protein

Protein	Length	C1-like domain superfamily	Ssl1-like	TFIIH C1-like domain	TFIIH subunit Ssl1/p44	von Willebrand factor A-like domain superfamily	von Willebrand factor, type A	Zinc finger C2H2-type	Zinc finger, RING/FYVE/PHD-type
UniProtKB:Q7ZVV4 InterPro	392

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	gtf2h2-201 (1) Ensembl	Ensembl	1,888 nt	Select Tool ZFIN BLAST
ncRNA	gtf2h2-002 (1) Ensembl	Ensembl	1,848 nt	Select Tool ZFIN BLAST
ncRNA	gtf2h2-003 (1) Ensembl	Ensembl	796 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations