Gene

otop1

ID
ZDB-GENE-030131-1613
Name
otopetrin 1
Symbol
otop1 Nomenclature History
Previous Names
  • backstroke
  • bks
  • wu:fb76b02 (1)
  • zgc:103626
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Exhibits cholesterol binding activity; identical protein binding activity; and proton channel activity. Involved in otolith formation; otolith mineralization; and proton transmembrane transport. Localizes to integral component of membrane. Is expressed in otic vesicle; sensory system; and yolk syncytial layer. Orthologous to human OTOP1 (otopetrin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With otop1 Human Ortholog
No data available
Associated With otop1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004878 Otopetrin
Domain Details Per Protein
Protein Length Otopetrin
UniProtKB:Q7ZWK8 586
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations