Gene
fmnl3
- ID
- ZDB-GENE-030131-1571
- Name
- formin-like 3
- Symbol
- fmnl3 Nomenclature History
- Previous Names
-
- fb74h11
- si:ch73-60e21.1
- wu:fb74h11
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Involved in actin filament polymerization; filopodium assembly; and sprouting angiogenesis. Predicted to localize to cytosol. Is expressed in several structures, including cardiovascular system; digestive system; myotome; nervous system; and trunk. Orthologous to human FMNL3 (formin like 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR010472 | Formin, FH3 domain |
| Domain | IPR010473 | Formin, GTPase-binding domain |
| Domain | IPR014767 | Diaphanous autoregulatory (DAD) domain |
| Domain | IPR014768 | Rho GTPase-binding/formin homology 3 (GBD/FH3) domain |
| Domain | IPR015425 | Formin, FH2 domain |
| Family | IPR043592 | Formin-like protein, animal |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR042201 | Formin, FH2 domain superfamily |
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Diaphanous autoregulatory (DAD) domain | Formin, FH2 domain | Formin, FH2 domain superfamily | Formin, FH3 domain | Formin, GTPase-binding domain | Formin-like protein, animal | Rho GTPase-binding/formin homology 3 (GBD/FH3) domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AYJ0
|
1043 | |||||||||
|
UniProtKB:Q6NXC0
|
1047 | |||||||||
|
UniProtKB:A0A8M2B9E3
|
1038 | |||||||||
|
UniProtKB:A0A8M3AVH2
|
1002 |
Interactions and Pathways
No data available
Plasmids
No data available