Gene
tia1
- ID
- ZDB-GENE-030131-1506
- Name
- TIA1 cytotoxic granule-associated RNA binding protein
- Symbol
- tia1 Nomenclature History
- Previous Names
-
- fb73d10
- wu:fb73d10
- wu:fc02b04
- zgc:55520
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity. Orthologous to human TIA1 (TIA1 cytotoxic granule associated RNA binding protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55520 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| amyotrophic lateral sclerosis type 26 | Alliance | Amyotrophic lateral sclerosis 26 with or without frontotemporal dementia | 619133 |
| Welander distal myopathy | 604454 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR003954 | RNA recognition motif domain, eukaryote |
| Domain | IPR034827 | TIA-1, RNA recognition motif 1 |
| Domain | IPR034830 | TIA-1, RNA recognition motif 2 |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | RNA recognition motif domain, eukaryote | TIA-1, RNA recognition motif 1 | TIA-1, RNA recognition motif 2 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3ASR4
|
256 | ||||||
|
UniProtKB:Q7ZVY0
|
386 | ||||||
|
UniProtKB:A0A8M3AZZ3
|
385 |
Interactions and Pathways
No data available
Plasmids
No data available